Pulmonary alveolar proteinosis: infiltrative lung diseases: merck ...
Pulmonary alveolar proteinosis. Onary Function Testing) reveal that the volume of air that the lungs can hold is abnormally small. Tests show low levels of oxygen in the blood, at first only during exercise but later also at rest. Even breathing pure oxygen results in well below the expected level of oxygen in the blood. Blood test results are not specific, although levels of some substances (for example, lactic dehydrogenase LDH and gamma globulin levels) are often elevated. To make a definitive diagnosis, a doctor examines a sample of the fluid from the alveoli. To obtain a sample, a doctor uses a bronchoscope (see Symptoms and Diagnosis of Lung Disorders: Bronchoscopy) to wash segments of the lung with a salt solution and then collects the washings. Sometimes a doctor performs a lung biopsy (obtains a lung tissue sample for microscopic examination) during bronchoscopy. Occasionally, a larger specimen is needed, which must be removed surgically. Treatment People who have few or no symptoms do not require treatment. For those with disabling symptoms, the protein-rich fluid in the alveoli can be washed out with a salt solution during bronchoscopy or through a special tube inserted through the mouth into or through the windpipe (trachea). Sometimes only a small section of the lung must be washed, but if symptoms are severe and the levels of oxygen in the blood are very low, the person is given general anesthesia, so that one entire lung can be washed. About 3 to 5 days later, the other lung is washed, again with the person under general anesthesia. One washing is enough for some people, while others need w
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Pulmonary alveolar proteinosis
Ting factor for pulmonary alveolar proteinosis. Eur Respir J 27: 585-593 Abstract Full Text Joshi, P. C., Applewhite, L., Ritzenthaler, J. D., Roman, J., Fernandez, A. L., Eaton, D. C., Brown, L. A. S., Guidot, D. M. (2005). Chronic Ethanol Ingestion in Rats Decreases Granulocyte-Macrophage Colony-Stimulating Factor Receptor Expression and Downstream Signaling in the Alveolar Macrophage. J Immunol 175: 6837-6845 Abstract Full Text Centella, T., Oliva, E., Andrade, I. G., Epeldegui, A. (2005). The use of a membrane oxygenator with extracorporeal circulation in bronchoalveolar lavage for alveolar proteinosis. ICVTS 4: 447-449 Abstract Full Text Bonfield, T. L., John, N., Barna, B. P., Kavuru, M. S., Thomassen, M. J., Yen-Lieberman, B. (2005). Multiplexed Particle-Based Anti-Granulocyte Macrophage Colony Stimulating Factor Assay Used as Pulmonary Diagnostic Test. CVI 12: 821-824 Abstract Full Text Padilla, J., Daley, E., Chow, A., Robinson, K., Parthasarathi, K., McKenzie, A. N. J., Tschernig, T., Kurup, V. P., Donaldson, D. D., Grunig, G. (2005). IL-13 Regulates the Immune Response to Inhaled Antigens. J Immunol 174: 8097-8105 Abstract Full Text Tazawa, R., Hamano, E., Arai, T., Ohta, H., Ishimoto, O., Uchida, K., Watanabe, M., Saito, J., Takeshita, M., Hirabayashi, Y., Ishige, I., Eishi, Y., Hagiwara, K., Ebina, M., Inoue, Y., Nakata, K., Nukiwa, T. (2005). Granulocyte-Macrophage Colony-Stimulating Factor and Lung Immunity in Pulmonary Alveolar Proteinosis. Am J Respir Crit Care Med 171: 1142-1149 Abstract Full Text Bender, A. T., Ostenson, C. L., Wang, E. H., Beavo, J. A. (
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